BR had another neurologist appointment on Monday. They had the results of the brain MRIs, which showed no change when compared to the MRIs done last March. Yet the reduced cognitive ability, significant weight loss, loss of manual dexterity, and visual distortions are all new symptoms since then. Research seems to indicate that MRIs are a poor indicator for PPMS disease progression, and BR seems to be a classic example.
So what now? The neurologist doesn't feel that any of the disease modifying drugs will be of any benefit. We are just going to treat the symptoms and try to make BR as comfortable as possible. That treatment will include Solu-medrol infusions every 3 months, with the hope of increased strength, weight stabilization, and higher energy levels.